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Product trade name: Canesten Combi-Pak Cream 1
Pharmaceutical active ingredients containing related brand and generic drugs, medications or other health care products: Canesten Combi-Pak Cream 1 available forms, composition, doses: Canesten Combi-Pak Cream 1 destination | category: Indications and usages, anatomical therapeutic chemical and diseases classification codes: Pharmaceutical companies, researchers, developers, manufacturers, distributors and suppliers: Online pharmacy, drugstores, pharma, health and beauty shops selling this or related pharmaceutical products: There is an additional general information about this medication active ingredient clotrimazole: Pharmacological action Canesten Combi-Pak Cream 1 is an antifungal agent of imidazole derivatives group for topical use. This medication has an effect at the expense of the synthesis of ergosterol, which is part of the cell membrane of fungi. Clotrimazole has a broad spectrum of action. Canesten Combi-Pak Cream 1 is active against dermatophytes, molds, fungi of the genus Candida, Malassezia furfur. This drug is also active against Corynebacterium minutissimum, Streptococcus spp., Staphylococcus spp., Trichomonas vaginalis. Pharmacokinetics For external use clotrimazole is well into the various layers of the skin reaching therapeutic concentrations. When this medication applied topically a small amount of it absorbed into the bloodstream. Why is Canesten Combi-Pak Cream 1 prescribed? Fungal skin and mucous membranes: ringworm, tinea, trichophytosis, athlete, mikrosporiya, candidiasis, a fungal interdigital erosion, fungal paronychia; fungal infections complicated by a secondary pyoderma; colorful lichen, erythrasma; thrush; Candida vulvitis, vulvovaginitis, balanitis, trichomoniasis; for the renovation of the birth canal before delivery. Dosage and administration When Canesten Combi-Pak Cream 1 used externally it applied to affected skin 2-3 times / day in 2-4 weeks. For local orally this medicine used 1-2 times / day, no more than 7 days. Intravaginal - on 100-500 mg for 1-6 days. Canesten Combi-Pak Cream 1 side effects, adverse reactions Local reactions: contact allergic dermatitis, redness, burning sensation. When applied topically to the skin: erythema, blisters, swelling, burning and tingling, irritation and flaking skin. When applied topically for the treatment of urogenital infections: itching, burning, redness and swelling of the mucous membrane, vaginal discharge, frequent urination, intercurrent cystitis, burning sensation in the penis with a partner, pain during sexual intercourse. When applied topically in the oral cavity: redness of the oral mucosa, burning sensation and tingling at the site of application, irritation. Canesten Combi-Pak Cream 1 contraindications Hypersensitivity to clotrimazole, I trimester of pregnancy. Using during pregnancy and breastfeeding In experimental studies there have been found that clotrimazole used in high doses exerts embryotoxic effect. It is not known whether Canesten Combi-Pak Cream 1 released in breast milk. Although clotrimazole is not contraindicated during pregnancy and lactation, it should be considered a potential risk when selecting antifungal therapy. Special instructions Prescribed intravaginal Dosage forms of Canesten Combi-Pak Cream 1 is not used during menstruation. To prevent reinfection it should be simultaneous treatment of sexual partners. Clotrimazole is not recommended for use in ophthalmology. Canesten Combi-Pak Cream 1 drug interactions Simultaneous administration of Canesten Combi-Pak Cream 1 with amphotericin B, nystatin, natamycin activity of clotrimazole decreases. Canesten Combi-Pak Cream 1 in case of emergency / overdose Symptoms: anorexia, nausea, vomiting, stomachodynia, abnormal liver function, rarely - drowsiness, hallucinations, thamuria, allergic skin reactions. Treatment: taking activated charcoal, symptomatic therapy.
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