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Product trade name: Clearsing
Pharmaceutical active ingredients containing related brand and generic drugs, medications or other health care products: Clearsing available forms, composition, doses: Clearsing destination | category: Indications and usages, anatomical therapeutic chemical and diseases classification codes: Pharmaceutical companies, researchers, developers, manufacturers, distributors and suppliers: Online pharmacy, drugstores, pharma, health and beauty shops selling this or related pharmaceutical products: There is an additional general information about this medication active ingredient azithromycin: Pharmacological action Azithromycin is a macrolide antibiotic of azalides group. Clearsing inhibits RNA-dependent protein synthesis of sensitive microorganisms. It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. (including Streptococcus pneumoniae, Streptococcus pyogenes group A); gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis. Pharmacokinetics Clearsing rapidly absorbed from the gastrointestinal tract. Ingestion reduces the absorption of azithromycin. Cmax in plasma is reached after 2-3 hours. This medicine rapidly distributed in tissues and biological fluids. 35% of the azithromycin is metabolized in the liver by demethylation. More than 59% is excreted in the bile in unchanged form, about 4.5% in the urine in unchanged form. Why is Clearsing prescribed? Infectious-inflammatory diseases caused by microorganisms susceptible to azithromycin, including bronchitis, pneumonia, infections of skin and soft tissue, otitis media, sinusitis, pharyngitis, tonsillitis, gonorrheal and non gonorrheal urethritis and / or cervicitis, Lyme disease (borreliosis). Dosage and administration Dosage of Clearsing is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days. Clearsing side effects, adverse reactions Digestive system: nausea, vomiting, flatulence, diarrhea, abdominal pain, transient elevation of liver enzymes, rarely - cholestatic jaundice. Allergic reactions: rarely - a skin rash, angioedema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis. Dermatological reactions: rarely - photosensitization. CNS: dizziness, headache, rarely - drowsiness, weakness. Hematopoietic system: rarely - leukopenia, neutropenia, thrombocytopenia. Cardiovascular system: rarely - chest pain. Urogenital system: vaginitis, rarely - candidiasis, nephritis, increased residual nitrogen urea. Other: rarely - hyperglycemia, arthralgia. Contraindications Hypersensitivity to azithromycin and other macrolide antibiotics. Using during pregnancy and breastfeeding Azithromycin crosses the placental barrier. Use in pregnancy only in cases where the intended benefits to the mother outweighs the potential risk to the fetus. If necessary to use azithromycin in the lactation period should solve the issue of termination of breastfeeding. Special instructions Clearsing not recommended for use in patients with compromised liver function. Azithromycin uses with careful with impaired renal function. This medication should be taken at least 1 hour before or 2 hours after eating or taking of antacids. Clearsing drug interactions Simultaneous administration of azithromycin with these drugs and medications may has followed effects:
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