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Product trade name: Indomethacin



Pharmaceutical active ingredients containing related brand and generic drugs, medications or other health care products:

  • Indometacin

    Indomethacin available forms, composition, doses:

  • Capsules; Oral; Indometacin 25 mg
  • Capsules; Oral; Indometacin 50 mg

    Indomethacin destination | category:

  • Human:
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

    Indications and usages, anatomical therapeutic chemical and diseases classification codes:

  • C01EB03 - Indometacin
  • M01AB01 - Indometacin
  • M02AA23 - Indometacin
  • S01BC01 - Indometacin

    Pharmaceutical companies, researchers, developers, manufacturers, distributors and suppliers:

  • Pliva

    Online pharmacy, drugstores, pharma, health and beauty shops selling this or related pharmaceutical products:

  • Buy Indomethacin online

    There is an additional general information about this medication active ingredient indometacin:

    Indomethacin Pliva information

    Indomethacin Pliva is a non-steroidal anti-inflammatory drug, typically prescribed in order to manage symptoms such as pain, fever, swelling and stiffness. This medication acts as an inhibitor of prostaglandin production - prostaglandins are the agents that are known to induce these symptoms.

    Indomethacin Pliva indications

    There are several medical conditions for which Indomethacin Pliva may be prescribed, including rheumatoid arthritis, ankylosing spondylitis, arthritic gout, juvenile arthritis, osteoarthritis and psoriatic arthritis. Apart from these, this drug has shown positive results when prescribed for the treatment of Reiter's syndrome, Bartter syndrome and Paget's disease. Indomethacin Pliva may also be prescribed for patients that are suffering from pseudogout, pericarditis, dysmenorrheal, bursitis or tendonitis. This drug is also effective for the management of such affections as nephrogenic diabetes insipidus, hemicrania continua, paroxysmal hemicrania and migraine, but it may also be used in the management of symptoms such as pain and fever associated with malignancies (bony metastases, tumors or lymphogranulomatosis). There may be other uses for this medication as well.

    Indomethacin Pliva warnings

    The intake of Indomethacin Pliva is not suitable in the case of patients that are suffering from an allergy to this drug, to any of its components, to Aspirin or to other non-steroidal anti-inflammatory medications. Also, this drug should not be employed in the treatment of patients with concurrent peptic ulcers or with severe preexisting liver or kidney damage. In the case of neonates with patent ductus arteriosus, Indomethacin Pliva should not be employed in the treatment of children of less than 2 years of age.
    Caution should be employed in the treatment of patients suffering from Parkinson's disease, psychotic disorders or epilepsy as Indomethacin Pliva may worsen the symptoms of these conditions. Therapy with this medication may require special consideration when employed in the treatment of patients suffering from bleeding tendencies as Indomethacin Pliva may inhibit the aggregation of platelets. Frequent blood cell counts clinical evaluations are recommended in the case of patients with preexisting bone marrow damage.

    Indomethacin Pliva intake guidelines

    It is highly recommended that the patient closely follows the Indomethacin Pliva intake guidelines that he or she has been given by the prescribing doctor. In many cases, regular physical examination of the patient may be required, in order to detect early signs of oedema or any possible side effects affecting the central nervous system. Blood pressure should be measured in order to check for hypertension. As part of the regular testing, blood cell counts, serum electrolyte measurements of the sodium, chloride and potassium and assessment of renal and liver functions should be performed, especially in the case of patients that are being administered Indomethacin Pliva in combination with a potassium-sparing diuretic or an ACE inhibitor; this is useful in order to detect or prevent development of kidney failure or hyperkalemia.

    Indomethacin Pliva dosage

    The exact Indomethacin Pliva dosage depends on the medical condition that the individual is being treated for. Apart from that, the examining health care professional will decide the appropriate dosage based on several factors such as the patient's medical history, his or her age as well as general health condition. The Indomethacin Pliva dosage may vary greatly from one patient to another, so it is highly recommended that you use the exact dosage that has been prescribed in your case.



    Indomethacin Pliva overdose

    Indomethacin Pliva has a high factor of acute toxicity in humans, and in some cases an overdose with this drug resulted in the death of the patient. As such, it is highly advised to take the medication dosage that has been prescribed for your case, and never take a higher dose.
    Typical symptoms of a Indomethacin Pliva overdose include dizziness, drowsiness, mental confusion, severe headache, paraesthesia, nausea, vomiting and numbness of limbs. In some cases, severe gastrointestinal bleeding as well as cardiac arrest or cerebral oedema are possible.

    Indomethacin Pliva missed dose

    It is highly advised that you set up a regular intake schedule in order to lower the risks of missing a dose of your medication. In the case of Indomethacin Pliva, if you happen to miss a dose it is advised to take it as soon as you remember, unless it is almost time for another dose of the medication. If this is the case, you should completely skip the missed dose and continue with your regular intake schedule; you should bring the matter to the attention of your personal health care provider as soon as possible. He or she will assess the situation and decide on the appropriate course of action to take, if needed.

    Indomethacin Pliva side effects

    There are several side effects associated with a Indomethacin Pliva treatment. Treatment with this drug may lead to the appearance of peptic ulcers or other less severe gastrointestinal disturbances such as mild diarrhea, dyspepsia or heartburn. Due to the retention of lithium, patients following a treatment with Indomethacin Pliva have a higher risk of lithium toxicity. Hypertension, hyperkalemia and hypernatremia as well as oedema are also possible side effects of a therapy with this drug. In up to 20% of the cases, the patients may experience headaches, sometimes together with tinnitus, vertigo, dizziness, hearing loss or blurred vision. Photosensitivity and skin reactions have been reported. In rare cases, Indomethacin Pliva may cause severe damage to the bone marrow, severe or even lethal hepatitis or potentially fatal shock.

    Indomethacin Pliva drug reactions

    At this time, there is no exact information regarding the possible interactions between Indomethacin Pliva and other medications. It is advised that you consult with your personal health care professional and inform him or her about any other medication you are currently taking before starting a treatment with this drug.



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