No two people are the same, but I've alywas had a sensitive stomach and have never had any problems taking this product over the last few months. I initially purchased a bottle as part of a new fitness regimen, and my results were regular and voluminous. (The first few days were particularly productive.) Never any diarrhea, never any bloating. Just the best digestive health and regularity of my life, though keep in mind I'm pairing its use with better diet and regular exercise. Can't recommend this stuff highly enough.